Schwörer S*, Cimino FV, Ros M, Tsanov KM, Ng C, Lowe SW, Carmona-Fontaine C, Thompson CB*. Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines. Cancer Research. 2023 May 15;83(10):1596-1610. *Co-corresponding authors

Highlighted as Research Highlight in Cancer Research. 2023;3: 1560

Schwörer S, Pavlova NN, Cimino FV, King B, Cai X, Sizemore GM, Thompson CB. Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment. Nature Metabolism. 2021 Nov;3(11):1484-1499. PMID: 34764457.

Highlighted as News & Views in Nature Metabolism. 2021;3: 1439–1440. PMID: 34764458

Highlighted as Breaking Insight in Cancer Research. 2022;82(2): 185-186

Zhu J, Schwörer S, Berisa M, Kyung YJ, Ryu KW, Yi J, Jiang X, Cross JR, Thompson CB. Mitochondrial NADP(H) generation is essential for proline biosynthesis. Science. 2021 May 28; 372(6545): 968-972. PMID: 33888598

Schwörer S, Berisa M, Violante S, Qin W, Zhu J, Hendrickson RC, Cross JR, Thompson CB. Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress. EMBO Journal. 2020 Apr 15;39(8):e103334. PMID: 32134147

Zhu J, Berisa M, Schwörer S, Qin W, Cross JR, Thompson CB. Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation. Cell Metabolism. 2019 Nov 5;30(5):865-876.e5. PMID: 31607565

Schwörer S, Vardhana SA, Thompson CB. Cancer Metabolism Drives a Stromal Regenerative Response. Cell Metabolism. 2019 Mar 5;29(3):576-591. PMID: 30773467

Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B, Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL, Kestler HA, Neri F, von Maltzahn J, Tümpel S, Rudolph KL. Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals. Nature. 2016 Dec 15;540(7633):428-432. PMID: 27919074

Highlighted as News & Views in Nature. 2016;540: 349-350

Rinkenauer AC, Press AT, Raasch M, Pietsch C, Schweizer S, Schwörer S, Rudolph KL, Mosig A, Bauer M, Traeger A, Schubert US. Comparison of the uptake of methacrylate-based nanoparticles in static and dynamic in vitro systems as well as in vivo. Journal of Control Release. 2015 Oct 28;216:158-68. PMID: 26277064

Pre-prints

Schwörer S, Ros M, Tsanov KM, Cimino FV, Lowe SW, Carmona-Fontaine C, Thompson CB. Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines. bioRxiv. doi.org/10.1101/2022.07.26.501639

Book Chapters

Schwörer S, Tümpel S. Molecular Mechanisms of Muscle Stem Cell Aging. Rudolph K, editor. Adult Stem Cells in Aging, Diseases and Cancer. Karger; 2015; p.25-39